南京大学医学院-j9集团

杨中州博士
教授
电话:邮箱:zhongzhouyang@nju.edu.cn 地址:汉口路22号研究方向:

心脏发育与先天性心脏病

  • 个人简介
  • 学术兼职
  • 代表性论文
  • 承担科研项目
  • 获奖情况

1997年于北京大学医学部获得医学硕士学位;1998年作为访问学者在美国宾夕法尼亚大学工作学习;

2004年于瑞士巴塞尔大学/弗里德里奇-米歇尔生物医学研究所获得博士学位;2005年进入南京大学工作。


中国细胞生物学会常务理事,发育生物学分会会长;国家心血管病专家委员会先心病专业委员会常委


1. ke zhao, xinyi huang, wukui zhao, bin lu and zhongzhou yang* (2022) lonp1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. development

2. yingchao shi, wenli fan, mingjie xu, xinhua lin, wukui zhao* and zhongzhou yang* (2022) critical role of znhit1 for postnatal heart function and vacuolar cardiomyopathy. jci insight

3. xinyi huang, ke zhao, mingyang jiang, dehui qiu, jun zhou and zhongzhou yang* (2022) the g4 resolvase rhau regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms. j. biol. chem.

4. mingjie xu, jie yao, yingchao shi, huijuan yi, wukui zhao, xinhua lin* and zhongzhou yang*. (2021) the srcap chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. development (亮点文章)

5. meng xia, wen luo, hengwei jin and zhongzhou yang*. (2019) hand2-mediated epithelial maintenance and integrity in cardiac outflow tract morphogenesis. development.(封面文章)

6. hengwei jin, huijuan wang, jie li, shan yu, mingjie xu, zhiqian qiu, meng xia, jingai zhu, qiuting feng, jun xie, biao xu and zhongzhou yang*. (2019)differential contribution of the two waves of cardiac progenitors and their derivatives to aorta and pulmonary artery. dev. biol.

7. jisheng hu, yingchao shi, meng xia, zhongying liu, ruirui zhang, hongmei luo, tongcun zhang, zhongzhou yang* and baiyin yuan*. (2018) wdr1-regulated actin dynamics is required for outflow tract and right ventricle development. dev. biol.

8. qi xiao, guoxin zhang, huijuan wang, lai chen, shuangshuang lu, dejing pan, geng liu*andzhongzhou yang*. (2017) a p53 based genetic tracing system to follow postnatal cardiomyocyte expansion in heart regeneration. development(亮点文章/封面文章)

9. wen luo, xia zhao, hengwei jin, lichan tao, jingai zhu, huijuan wang, brian a. hemmings and zhongzhou yang*. (2015) akt1 signaling coordinates bmp signaling and β-catenin activity to regulate second heart field progenitor development. development.

10. junwei nie, mingyang jiang, xiaotian zhang, hao tang, hengwei jin, xinyi huang, baiyin yuan, chenxi zhang, janice ching lai, yoshikuni nagamine, dejing pan, wengong wang* and zhongzhou yang*. (2015) post-transcriptional regulation of nkx2-5 by rhau in heart development.cell rep.(封面文章)

11. xia zhao, shuangshuang lu, junwei nie, xiaoshan hu, wen luo, xiangqi wu, hailang liu, qiuting feng, zai chang, yaoqiu liu, yunshan cao, haixiang sun, xinli li, yali hu, zhongzhou yang*. (2014) phosphoinositide-dependent kinase 1 and mtorc2 synergisticallymaintain postnatal heart growth and heart function in mice. mol. cell. biol.(亮点/封面文章)

12. qiuting feng, ruomin di, fang tao, zai chang, shuangshuang lu, wenjing fan, congjia   shan, xinli li* and zhongzhou yang*. (2010) pdk1 regulates vascular remodeling and promotes epithelial-mesenchymal transition in cardiac development. mol. cell. biol.(亮点文章)

13. zai chang, qin zhang, qiuting feng, jie xu, teng teng, qing luan, congjia shan, yali hu, brian a hemmings, xiang gao andzhongzhou yang*. (2010) deletion of akt1 causes heart defects and abnormal cardiomyocyte proliferation. dev. biol.


主持在研项目:1.国家自然科学基金重点项目一项;3. 科技部“发育编程及其代谢调节”重点研发专项项目一项。

国家科技进步奖二等奖(2016, 排名第3)

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